DOTQUINE is a combination of Quinapyramine Sulphate and Quinapyramine Chloride salts. These two salts are active Trypanocidal but differ greatly in their solubility and the rate of absorption from the site of injection.
Sulphate salt is readily soluble in water and provides curative action
Chloride salt is comparatively insoluble in water and forms a depot at the site of injection from where it is slowly absorbed into the systemic circulation and thus provides prophylatic action in treatment of Trypanosomiasis in cattle, buffaloes, elephants, camels, horses and dogs after administration
Each vial (2.5 g) contains:
Quinapyramine Sulphate B. Vet.C. 1.5 g.
Quinapyramine Chloride B. Vet.C. 1.0 g.
DOSE & ROUTE OF ADMINISTRATION:
By S.C route generally as 10% suspension
By I.M route if it is 5% suspension
In cattle, the common sites are behind the shoulder, the mid-line of dewlap, or the caudal fold.
In horses, the normal site is in front of the shoulder.
PREPARATION OF SUSPENSION:
2.5 gm to be mixed in 15ml water for injection. The reconstituted suspension should be shaken well and should be used IMMEDIATELY.
CATTLE / BUFFALOES / HORSES / CAMELS / ELEPHANTS / DOGS:
10 Kg 100 mg 0.6 ml
20 Kg 200 mg 1.2 ml
100 Kg 1 gm 6 ml
150 Kg 1.5 gm 9 ml
350 Kg & above 2.5 gm 15 ml
Vial containing 2.5gm DOTQUINE including Tray & 20 ml Sterile Water.
SCHEDULE ‘H’ PRESCRIPTION DRUG